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Christopher G. Rylander
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Proceedings Papers

Evaluation of Pressure Sensors in a Novel Neonatal Multifunctional Gastric Feeding Tube Capable of Vital Sign Monitoring

Iman Salafian, Lynn El Dana, Angie Englert, Wei Li, Alan Groves, Christopher G. Rylander
Proc. ASME. DMD2024, 2024 Design of Medical Devices Conference, V001T09A008, April 8–10, 2024
Publisher: American Society of Mechanical Engineers
Paper No: DMD2024-1060
https://doi.org/10.1115/DMD2024-1060
View Paper titled, Evaluation of Pressure Sensors in a Novel Neonatal Multifunctional Gastric Feeding Tube Capable of Vital Sign Monitoring
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Topics: Continuous positive airway pressure, Flow (Dynamics), Pressure, Pressure sensors, Sensors, Catheters, Noise (Sound), Feedback, Pressure measurement, Signals
Proceedings Papers

Evaluating the Effectiveness of a Novel, Rapidly Appliable Multifunctional Pulse Oximeter in Neonatal Care

Iman Salafian, Davika Reid, Morgan E Laird, Christopher Klunk, Christopher G. Rylander
Proc. ASME. DMD2024, 2024 Design of Medical Devices Conference, V001T09A007, April 8–10, 2024
Publisher: American Society of Mechanical Engineers
Paper No: DMD2024-1059
https://doi.org/10.1115/DMD2024-1059
View Paper titled, Evaluating the Effectiveness of a Novel, Rapidly Appliable Multifunctional Pulse Oximeter in Neonatal Care
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Topics: Adhesives, Blood, Fasteners, Oxygen, Performance, Risk, Safety, Sensors, Skin, Temperature
Proceedings Papers

DEVELOPMENT AND TESTING OF A MULTIFUNCTION GASTRIC FEEDING TUBE CAPABLE OF VITAL SIGN MONITORING

Iman Salafian, Angie Englert, Allissa Morris, Alan Groves, Christopher G. Rylander
Proc. ASME. DMD2023, 2023 Design of Medical Devices Conference, V001T09A005, April 17–19, 2023
Publisher: American Society of Mechanical Engineers
Paper No: DMD2023-1926
https://doi.org/10.1115/DMD2023-1926
View Paper titled, DEVELOPMENT AND TESTING OF A MULTIFUNCTION GASTRIC FEEDING TUBE CAPABLE OF VITAL SIGN MONITORING
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Journal Articles

Solid Fiber Inside of Capillary and Modified Fusion-Spliced Fiber Optic Microneedle Devices for Improved Light Transmission Efficiency

Jason N. Mehta, Brianna E. Morales, John H. Rossmeisl, Waldemar Debinski, Christopher G. Rylander
Journal: Journal of Medical Devices
Publisher: ASME
Article Type: Research-Article
J. Med. Devices. December 2022, 16(4): 041014.
Paper No: MED-22-1049
https://doi.org/10.1115/1.4055607
Published Online: September 27, 2022
View Article titled, Solid Fiber Inside of Capillary and Modified Fusion-Spliced Fiber Optic Microneedle Devices for Improved Light Transmission Efficiency
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Topics: Fibers, Microneedles, Manufacturing
Journal Articles

Constant Pressure Convection-Enhanced Delivery Increases Volume Dispersed With Catheter Movement in Agarose

Jason N. Mehta, Brianna E. Morales, Fang-Chi Hsu, John H. Rossmeisl, Christopher G. Rylander
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. November 2022, 144(11): 111003.
Paper No: BIO-21-1376
https://doi.org/10.1115/1.4054729
Published Online: June 16, 2022
View Article titled, Constant Pressure Convection-Enhanced Delivery Increases Volume Dispersed With Catheter Movement in Agarose
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Topics: Agar, Catheters, Flow (Dynamics), Pressure, Convection
Proceedings Papers

Evaluating The Dispersal Volume of a Six-Port Arborizing Catheter in Agarose as a Function of Infusion Flow Rate and Catheter Retraction Speed

Etse-Oghena Y. Campbell, Fang-Chi Hsu, Christopher G. Rylander
Proc. ASME. DMD2022, 2022 Design of Medical Devices Conference, V001T10A005, April 11–14, 2022
Publisher: American Society of Mechanical Engineers
Paper No: DMD2022-1057
https://doi.org/10.1115/DMD2022-1057
View Paper titled, Evaluating The Dispersal Volume of a Six-Port Arborizing Catheter in Agarose as a Function of Infusion Flow Rate and Catheter Retraction Speed
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Topics: Agar, Catheters, Convection, Flow (Dynamics)
Proceedings Papers

Convection-Enhanced Thermo-Therapy Catheter System: Microneedle Compression Strength Testing with Various Durometers

Brianna E. Morales, Christopher G. Rylander
Proc. ASME. DMD2022, 2022 Design of Medical Devices Conference, V001T05A007, April 11–14, 2022
Publisher: American Society of Mechanical Engineers
Paper No: DMD2022-1067
https://doi.org/10.1115/DMD2022-1067
View Paper titled, Convection-Enhanced Thermo-Therapy Catheter System: Microneedle Compression Strength Testing with Various Durometers
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Topics: Catheters, Compressive strength, Convection, Microneedles, Patient treatment, Testing
Proceedings Papers

Burst, Leakage, and Constant Pressure Infusion Testing of a Convection Enhanced Drug Delivery System for Glioblastoma Treatment

Iman Salafian, Christopher G. Rylander
Proc. ASME. DMD2022, 2022 Design of Medical Devices Conference, V001T10A006, April 11–14, 2022
Publisher: American Society of Mechanical Engineers
Paper No: DMD2022-1060
https://doi.org/10.1115/DMD2022-1060
View Paper titled, Burst, Leakage, and Constant Pressure Infusion Testing of a Convection Enhanced Drug Delivery System for Glioblastoma Treatment
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Topics: Catheters, Convection, Drug delivery systems, Fibers, Flow (Dynamics), Food and Drug Administration, Frequency-domain analysis, Leakage, Microneedles, Pressure
Proceedings Papers

Measuring Line Pressure in Convection-Enhanced Delivery Infusions

Jason N. Mehta, Brianna E. Morales, Christopher G. Rylander
Proc. ASME. DMD2021, 2021 Design of Medical Devices Conference, V001T12A012, April 12–15, 2021
Publisher: American Society of Mechanical Engineers
Paper No: DMD2021-1083
https://doi.org/10.1115/DMD2021-1083
View Paper titled, Measuring Line Pressure in Convection-Enhanced Delivery Infusions
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Topics: Convection, Pressure
Proceedings Papers

Helical Needle Suture Inserter Provides Increased Suture Retention Force Compared to a Straight Needle

Etse-Oghena Y. Campbell, Christopher G. Rylander
Proc. ASME. DMD2021, 2021 Design of Medical Devices Conference, V001T12A016, April 12–15, 2021
Publisher: American Society of Mechanical Engineers
Paper No: DMD2021-1089
https://doi.org/10.1115/DMD2021-1089
View Paper titled, Helical Needle Suture Inserter Provides Increased Suture Retention Force Compared to a Straight Needle
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Topics: Biological tissues, Needles, Phantoms
Proceedings Papers

Computational Model of a Two Material Object Predicts Non-Symmetric Dispersal Volume Profile

Brianna E. Morales, Jason N. Mehta, Christopher G. Rylander
Proc. ASME. DMD2021, 2021 Design of Medical Devices Conference, V001T12A014, April 12–15, 2021
Publisher: American Society of Mechanical Engineers
Paper No: DMD2021-1087
https://doi.org/10.1115/DMD2021-1087
View Paper titled, Computational Model of a Two Material Object Predicts Non-Symmetric Dispersal Volume Profile
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Topics: Computer simulation, Convection, Microneedles
Journal Articles

Convection-Enhanced Arborizing Catheter System Improves Local/Regional Delivery of Infusates Versus a Single-Port Catheter in Ex Vivo Porcine Brain Tissue

Egleide Y. Elenes, Jason N. Mehta, Fang-Chi Hsu, Christopher T. Whitlow, Waldermar Debinski, John Rossmeisl, Stephen Tatter, Christopher G. Rylander
Journal: Journal of Engineering and Science in Medical Diagnostics and Therapy
Publisher: ASME
Article Type: Research-Article
ASME J of Medical Diagnostics. February 2021, 4(1): 011003.
Paper No: JESMDT-20-1011
https://doi.org/10.1115/1.4048935
Published Online: December 2, 2020
View Article titled, Convection-Enhanced Arborizing Catheter System Improves Local/Regional Delivery of Infusates Versus a Single-Port Catheter in Ex Vivo Porcine Brain Tissue
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Topics: Biological tissues, Brain, Catheters, Microneedles, Convection
Proceedings Papers

Solid Fiber Inside Capillary and Modified Fusion-Spliced Fiber Optic Microneedle Devices

Jason N. Mehta, Christopher G. Rylander
Proc. ASME. DMD2020, 2020 Design of Medical Devices Conference, V001T10A010, April 6–9, 2020
Publisher: American Society of Mechanical Engineers
Paper No: DMD2020-9050
https://doi.org/10.1115/DMD2020-9050
View Paper titled, Solid Fiber Inside Capillary and Modified Fusion-Spliced Fiber Optic Microneedle Devices
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Topics: Fibers, Microneedles, Lasers, Manufacturing, Brain, Failure, Fluids, Catheters, Convection, Drug delivery systems
Proceedings Papers

Novel Method and Device for Delivery and Retention of Intrauterine Devices in the Immediate Postpartum Period: Pilot Baboon Feasibility Study

Etse-Oghena Campbell, Christopher G. Rylander, Lauren Thaxton, Marian Yvette Williams-Brown
Proc. ASME. DMD2020, 2020 Design of Medical Devices Conference, V001T10A009, April 6–9, 2020
Publisher: American Society of Mechanical Engineers
Paper No: DMD2020-9049
https://doi.org/10.1115/DMD2020-9049
View Paper titled, Novel Method and Device for Delivery and Retention of Intrauterine Devices in the Immediate Postpartum Period: Pilot Baboon Feasibility Study
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Topics: Safety
Journal Articles

Parametric Study of the Design Variables of an Arborizing Catheter on Dispersal Volume Using a Biphasic Computational Model

Egleide Y. Elenes, Manuel K. Rausch, Christopher G. Rylander
Journal: Journal of Engineering and Science in Medical Diagnostics and Therapy
Publisher: ASME
Article Type: Research-Article
ASME J of Medical Diagnostics. August 2019, 2(3): 031002.
Paper No: JESMDT-18-1066
https://doi.org/10.1115/1.4042874
Published Online: April 1, 2019
View Article titled, Parametric Study of the Design Variables of an Arborizing Catheter on Dispersal Volume Using a Biphasic Computational Model
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Topics: Agar, Biological tissues, Catheters, Cavities, Convection, Design, Flow (Dynamics), Gates (Closures), Pressure, Simulation
Proceedings Papers

Mechanical Compression for Dehydration and Optical Clearing of Skin

Chris W. Drew, Christopher G. Rylander
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 803-804, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-193017
https://doi.org/10.1115/SBC2008-193017
View Paper titled, Mechanical Compression for Dehydration and Optical Clearing of Skin
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Topics: Biological tissues, Compression, Electromagnetic scattering, Fibers, Light scattering, Proteins, Radiation scattering, Refractive index, Scattering (Physics), Skin
Journal Articles

Influence of Hyperthermia on Efficacy and Uptake of Carbon Nanohorn-Cisplatin Conjugates

Matthew R. DeWitt, Allison M. Pekkanen, John Robertson, Christopher G. Rylander, Marissa Nichole Rylander
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2014, 136(2): 021003.
Paper No: BIO-13-1471
https://doi.org/10.1115/1.4026318
Published Online: February 5, 2014
View Article titled, Influence of Hyperthermia on Efficacy and Uptake of Carbon Nanohorn-Cisplatin Conjugates
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Topics: Carbon, Drugs, Heat, Nanoparticles, Tumors, Temperature, Heating, Particulate matter, Patient treatment, Diffusion (Physics)
Proceedings Papers

Coupled Poroviscoelastic and Optical Monte Carlo Simulation of Dynamic Light Transport Through Indented Soft Tissue

William C. Vogt, Christopher G. Rylander
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT36A004, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14683
https://doi.org/10.1115/SBC2013-14683
View Paper titled, Coupled Poroviscoelastic and Optical Monte Carlo Simulation of Dynamic Light Transport Through Indented Soft Tissue
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Topics: Absorption, Biological tissues, Compression, Deformation, Electromagnetic scattering, Flow (Dynamics), Fluid dynamics, Proteins, Radiation scattering, Refractive index
Proceedings Papers

Fiberoptic Microneedle Probes for Tissue Penetration

Mehmet A. Kosoglu, Christopher G. Rylander
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 497-498, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206742
https://doi.org/10.1115/SBC2009-206742
View Paper titled, Fiberoptic Microneedle Probes for Tissue Penetration
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Topics: Biological tissues, Microneedles, Probes, Lasers, Absorption, Biomedicine, Coherence (Optics), Electromagnetic scattering, Imaging, Patient treatment
Proceedings Papers

Fluorescently Labeled Carbon Nanohorns as Intracellular Drug Delivery Vehicles

Kristen A. Zimmermann, David Inglefield, Timothy E. Long, Christopher G. Rylander, M. Nichole Rylander
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 635-636, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80818
https://doi.org/10.1115/SBC2012-80818
View Paper titled, Fluorescently Labeled Carbon Nanohorns as Intracellular Drug Delivery Vehicles
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Topics: Carbon, Drug delivery systems, Vehicles, Nanomaterials, Anticancer drugs, Biomedicine, Drugs, Lasers, Patient treatment, Shapes