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Journal Articles

In Vivo Quantification of Ascending Thoracic Aortic Aneurysm Wall Stretch Using MRI: Relationship to Repair Threshold Diameter and Ex Vivo Wall Failure Behavior

Huiming Dong, Henrik Haraldsson, Joseph Leach, Ang Zhou, Megan Ballweber, Chengcheng Zhu, Yue Xuan, Zhongjie Wang, Michael Hope, Frederick H. Epstein, Liang Ge, David Saloner, Elaine Tseng, Dimitrios Mitsouras
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. December 2024, 146(12): 121009.
Paper No: BIO-23-1137
https://doi.org/10.1115/1.4066430
Published Online: October 3, 2024
View Article titled, In Vivo Quantification of Ascending Thoracic Aortic Aneurysm Wall Stretch Using MRI: Relationship to Repair Threshold Diameter and Ex Vivo Wall Failure Behavior
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Topics: Aneurysms, Aorta, Displacement, Echoes, Encryption, Failure, Imaging, Magnetic resonance imaging, Maintenance, Mechanical testing
Includes: Supplementary data
Journal Articles

Atherosclerotic Calcifications Have a Local Effect on the Peel Behavior of Human Aortic Media

Carly L. Donahue, Ruturaj M. Badal, Thomas S. Younger, Weihua Guan, Elena G. Tolkacheva, Victor H. Barocas
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2024, 146(6): 061003.
Paper No: BIO-23-1319
https://doi.org/10.1115/1.4064682
Published Online: March 25, 2024
View Article titled, Atherosclerotic Calcifications Have a Local Effect on the Peel Behavior of Human Aortic Media
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Topics: Atherosclerosis, Tension, Oscillations, Aorta, Failure
Includes: Supplementary data
Journal Articles

Primary Mouse Aortic Smooth Muscle Cells Exhibit Region- and Sex-Dependent Biological Responses In Vitro

Niyousha Karbasion, Yujun Xu, J. Caleb Snider, Matthew R. Bersi
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2024, 146(6): 060904.
Paper No: BIO-23-1177
https://doi.org/10.1115/1.4064965
Published Online: March 20, 2024
View Article titled, Primary Mouse Aortic Smooth Muscle Cells Exhibit Region- and Sex-Dependent Biological Responses In Vitro
Open the PDF for Primary Mouse Aortic Smooth Muscle Cells Exhibit Region- and Sex-Dependent Biological Responses In Vitro in another window
Topics: Aorta, Muscle, Traction, Biological tissues, Microscopy, Chemical vapor deposition
Includes: Supplementary data
Journal Articles

Vascular Remodeling During Late-Gestation Pregnancy: An In-Vitro Assessment of the Murine Ascending Thoracic Aorta

Ana I. Vargas, Samar A. Tarraf, Turner Jennings, Chiara Bellini, Rouzbeh Amini
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. July 2024, 146(7): 071004.
Paper No: BIO-23-1351
https://doi.org/10.1115/1.4064744
Published Online: March 19, 2024
View Article titled, Vascular Remodeling During Late-Gestation Pregnancy: An In-Vitro Assessment of the Murine Ascending Thoracic Aorta
Open the PDF for Vascular Remodeling During Late-Gestation Pregnancy: An In-Vitro Assessment of the Murine Ascending Thoracic Aorta in another window
Topics: Aorta, Biological tissues, Blood, Hemodynamics, Pressure, Stiffness, Stress, Biomechanics, Wall thickness, Physiology
Journal Articles

Constitutive Modeling of Mouse Arteries Suggests Changes in Directional Coupling and Extracellular Matrix Remodeling That Depend on Artery Type, Age, Sex, and Elastin Amounts

Keshav A. Kailash, Jie Z. Hawes, Austin J. Cocciolone, Matthew R. Bersi, Robert P. Mecham, Jessica E. Wagenseil
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2024, 146(6): 060901.
Paper No: BIO-23-1046
https://doi.org/10.1115/1.4063272
Published Online: March 7, 2024
View Article titled, Constitutive Modeling of Mouse Arteries Suggests Changes in Directional Coupling and Extracellular Matrix Remodeling That Depend on Artery Type, Age, Sex, and Elastin Amounts
Open the PDF for Constitutive Modeling of Mouse Arteries Suggests Changes in Directional Coupling and Extracellular Matrix Remodeling That Depend on Artery Type, Age, Sex, and Elastin Amounts in another window
Topics: Anisotropy, Aorta, Biological tissues, Biomechanics, Cardiovascular system, Constitutive equations, Deformation, Fibers, Mechanical behavior, Mechanical testing
Includes: Supplementary data
Journal Articles

Layer-Specific Properties of the Human Infra-Renal Aorta During Aging Considering Pre/Post-Failure Damage

Dimitrios P. Sokolis
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2024, 146(2): 021003.
Paper No: BIO-23-1144
https://doi.org/10.1115/1.4064146
Published Online: December 12, 2023
View Article titled, Layer-Specific Properties of the Human Infra-Renal Aorta During Aging Considering Pre/Post-Failure Damage
Open the PDF for Layer-Specific Properties of the Human Infra-Renal Aorta During Aging Considering Pre/Post-Failure Damage in another window
Topics: Aorta, Failure, Stress, Kidney, Strips, Damage, Rupture
Includes: Supplementary data
Journal Articles

Simulating Subject-Specific Aortic Hemodynamic Effects of Valvular Lesions in Rheumatic Heart Disease

Hannah L. Cebull, Olukayode O. Aremu, Radhika S. Kulkarni, Samuel X. Zhang, Petronella Samuels, Stephen Jermy, Ntobeko A.B. Ntusi, Craig J. Goergen
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. November 2023, 145(11): 111003.
Paper No: BIO-23-1101
https://doi.org/10.1115/1.4063000
Published Online: August 2, 2023
View Article titled, Simulating Subject-Specific Aortic Hemodynamic Effects of Valvular Lesions in Rheumatic Heart Disease
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Topics: Aorta, Blood flow, Computational fluid dynamics, Diseases, Flow (Dynamics), Hemodynamics, Shear (Mechanics), Shear stress, Simulation, Statistical analysis
Includes: Supplementary data
Journal Articles

A Computational Model of Ventricular Dimensions and Hemodynamics in Growing Infants

Ashley A. Hiebing, Riley G. Pieper, Colleen M. Witzenburg
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. October 2023, 145(10): 101007.
Paper No: BIO-22-1295
https://doi.org/10.1115/1.4062779
Published Online: July 14, 2023
View Article titled, A Computational Model of Ventricular Dimensions and Hemodynamics in Growing Infants
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Topics: Aorta, Blood, Computer simulation, Dimensions, Hemodynamics, Pressure, Simulation, Weight (Mass)
Includes: Supplementary data
Journal Articles

Layer-Specific Tensile Strength of the Human Aorta: Segmental Variations

Dimitrios P. Sokolis
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. June 2023, 145(6): 064502.
Paper No: BIO-22-1253
https://doi.org/10.1115/1.4056748
Published Online: February 6, 2023
View Article titled, Layer-Specific Tensile Strength of the Human Aorta: Segmental Variations
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Topics: Aorta, Failure, Rupture, Strips, Stress, Biological tissues
Includes: Supplementary data
Journal Articles

A Computational Study of Dynamic Obstruction in Type B Aortic Dissection

T. Kim, P. A. J. van Bakel, N. Nama, N. Burris, H. J. Patel, D. M. Williams, C. A. Figueroa
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. March 2023, 145(3): 031008.
Paper No: BIO-22-1176
https://doi.org/10.1115/1.4056355
Published Online: December 21, 2022
View Article titled, A Computational Study of Dynamic Obstruction in Type B Aortic Dissection
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Topics: Blood, Flow (Dynamics), Pressure, Simulation, Displacement, Hemodynamics, Vessels, Aorta, Boundary-value problems
Journal Articles

svMorph: Interactive Geometry-Editing Tools for Virtual Patient-Specific Vascular Anatomies

Jonathan Pham, Sofia Wyetzner, Martin R. Pfaller, David W. Parker, Doug L. James, Alison L. Marsden
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. March 2023, 145(3): 031001.
Paper No: BIO-22-1143
https://doi.org/10.1115/1.4056055
Published Online: December 5, 2022
View Article titled, svMorph: Interactive Geometry-Editing Tools for Virtual Patient-Specific Vascular Anatomies
Open the PDF for svMorph: Interactive Geometry-Editing Tools for Virtual Patient-Specific Vascular Anatomies in another window
Topics: Aneurysms, Engineering simulation, Geometry, Hemodynamics, Shapes, Simulation, Deformation, Aorta, Computational fluid dynamics, Modeling
Journal Articles

Feasibility of Vascular Parameter Estimation for Assessing Hypertensive Pregnancy Disorders

Georgios Kissas, Eileen Hwuang, Elizabeth W. Thompson, Nadav Schwartz, John A. Detre, Walter R. Witschey, Paris Perdikaris
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. December 2022, 144(12): 121011.
Paper No: BIO-22-1060
https://doi.org/10.1115/1.4055679
Published Online: October 28, 2022
View Article titled, Feasibility of Vascular Parameter Estimation for Assessing Hypertensive Pregnancy Disorders
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Topics: Aorta, Flow (Dynamics), Magnetic resonance imaging, Pressure, Vessels, Waves, Geometry, Algorithms
Journal Articles

Reducing Geometric Uncertainty in Computational Hemodynamics by Deep Learning-Assisted Parallel-Chain MCMC

Pan Du, Jian-Xun Wang
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. December 2022, 144(12): 121009.
Paper No: BIO-22-1104
https://doi.org/10.1115/1.4055809
Published Online: October 17, 2022
View Article titled, Reducing Geometric Uncertainty in Computational Hemodynamics by Deep Learning-Assisted Parallel-Chain MCMC
Open the PDF for Reducing Geometric Uncertainty in Computational Hemodynamics by Deep Learning-Assisted Parallel-Chain MCMC in another window
Topics: Algorithms, Aorta, Chain, Computational fluid dynamics, Flow (Dynamics), Hemodynamics, Modeling, Simulation, Uncertainty, Artificial neural networks
Journal Articles

Quantifying the Effect of Body Habitus on Cardiac Auscultation Via Computational Hemoacoustics

David Hojun Lee, Jung-Hee Seo, Rajat Mittal
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. February 2023, 145(2): 024503.
Paper No: BIO-22-1165
https://doi.org/10.1115/1.4055513
Published Online: October 6, 2022
View Article titled, Quantifying the Effect of Body Habitus on Cardiac Auscultation Via Computational Hemoacoustics
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Topics: Blood flow, Elastic waves, Emission spectroscopy, Hemodynamics, Signals, Simulation, Spectroscopy, Valves, Computational methods, Modeling
Journal Articles

Optimizing the Porohyperelastic Response of a Layered Compliance Matched Vascular Graft to Promote Luminal Self-Cleaning

Ali Behrangzade, Bruce R. Simon, William R. Wagner, Jonathan P. Vande Geest
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2023, 145(2): 021002.
Paper No: BIO-22-1025
https://doi.org/10.1115/1.4055563
Published Online: October 6, 2022
View Article titled, Optimizing the Porohyperelastic Response of a Layered Compliance Matched Vascular Graft to Promote Luminal Self-Cleaning
Open the PDF for Optimizing the Porohyperelastic Response of a Layered Compliance Matched Vascular Graft to Promote Luminal Self-Cleaning in another window
Topics: Aorta, Fluids, Optimization, Permeability, Simulation, Flow (Dynamics), Thrombosis, Geometry, Finite element analysis, Platelets
Journal Articles

Guiding the Prostatic Artery Embolization Procedure With Computational Fluid Dynamics

Mostafa Mahmoudi, Chadrick Jennings, Keith Pereira, Andrew F. Hall, Amirhossein Arzani
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. November 2022, 144(11): 111004.
Paper No: BIO-21-1381
https://doi.org/10.1115/1.4054515
Published Online: June 16, 2022
View Article titled, Guiding the Prostatic Artery Embolization Procedure With Computational Fluid Dynamics
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Topics: Aorta, Blood flow, Computational fluid dynamics, Hemodynamics, Particulate matter, Bifurcation, Flow (Dynamics)
Journal Articles

The Effects of Implantation Orientation of a Bileaflet Mechanical Heart Valve in an Anatomic Left Ventricle-Aorta Configuration

Hossein Asadi, Mohammadali Hedayat, Iman Borazjani
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. October 2022, 144(10): 101008.
Paper No: BIO-21-1436
https://doi.org/10.1115/1.4054411
Published Online: May 12, 2022
View Article titled, The Effects of Implantation Orientation of a Bileaflet Mechanical Heart Valve in an Anatomic Left Ventricle-Aorta Configuration
Open the PDF for The Effects of Implantation Orientation of a Bileaflet Mechanical Heart Valve in an Anatomic Left Ventricle-Aorta Configuration in another window
Topics: Aorta, Cycles, Flow (Dynamics), Kinematics, Shear stress, Valves, Heart valve prostheses, Platelets, Simulation
Journal Articles

Reduced Smooth Muscle Contractile Capacity Facilitates Maladaptive Arterial Remodeling

John F. Eberth, Jay D. Humphrey
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. April 2022, 144(4): 044503.
Paper No: BIO-21-1188
https://doi.org/10.1115/1.4052888
Published Online: December 15, 2021
View Article titled, Reduced Smooth Muscle Contractile Capacity Facilitates Maladaptive Arterial Remodeling
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Topics: Carotid arteries, Muscle, Pressure, Stress, Wall thickness, Stiffness, Biomechanics, Energy storage, Vessels, Aorta
Journal Articles

Computational Modeling of Aortic Stenosis With a Reduced Degree-of-Freedom Fluid-Structure Interaction Valve Model

Chi Zhu, Jung-Hee Seo, Rajat Mittal
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. March 2022, 144(3): 031012.
Paper No: BIO-20-1495
https://doi.org/10.1115/1.4052576
Published Online: November 3, 2021
View Article titled, Computational Modeling of Aortic Stenosis With a Reduced Degree-of-Freedom Fluid-Structure Interaction Valve Model
Open the PDF for Computational Modeling of Aortic Stenosis With a Reduced Degree-of-Freedom Fluid-Structure Interaction Valve Model in another window
Topics: Flow (Dynamics), Valves, Aorta, Fluid structure interaction, Degrees of freedom, Pressure
Journal Articles

Nicotine Affects Murine Aortic Stiffness and Fatigue Response During Supraphysiological Cycling

Elizabeth Ho, Joscha Mulorz, Jason Wong, Markus U. Wagenhäuser, Philip S. Tsao, Anand K. Ramasubramanian, Sang-Joon John Lee
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. January 2022, 144(1): 011005.
Paper No: BIO-21-1064
https://doi.org/10.1115/1.4051706
Published Online: September 1, 2021
View Article titled, Nicotine Affects Murine Aortic Stiffness and Fatigue Response During Supraphysiological Cycling
Open the PDF for Nicotine Affects Murine Aortic Stiffness and Fatigue Response During Supraphysiological Cycling in another window
Topics: Aorta, Fatigue, Stiffness, Stress, Biological tissues, Tension, Imaging, Cycles, Testing, Relaxation (Physics)
Includes: Supplementary data